Using Iron-Chelating Agents in Critically Ill Patients with Iron Overload. Fact or Fiction?
نویسندگان
چکیده
منابع مشابه
Endocrine Dysfunctions in Iron Overload in Patients with Major Thalassemia
Abstract Background The aim of the present study was to determine the endocrine dysfunction in patients with major thalassemia, who receive hyper transfusion. Materials and Methods This cross sectional study was performed during one year, which included 65 major thalassemia patients (31 females and 34 males), aged between 14 month to 27 years old (median 10,3). Growth assessment was measur...
متن کاملThe Effect of Combination Iron Chelating Agents on Reducing the Severity Grading of Heart and Liver Iron Overload in β-Thalassemia Patients
Background: Deferasirox (DFX), Deferoxamine (DFO), and Deferiprone (DFP) are iron chelators that can be used in thalassemic patients with iron overload. Materials and Methods: This clinical trial was performed on 108 thalassemic patients who were randomly divided into group A (n=54) and B (n=54). Group A received combination of DFX and DFP, and group B received DFO and DFP for six months. Seru...
متن کاملManagement of transfusional iron overload – differential properties and efficacy of iron chelating agents
Regular red cell transfusion therapy ameliorates disease-related morbidity and can be lifesaving in patients with various hematological disorders. Transfusion therapy, however, causes progressive iron loading, which, if untreated, results in endocrinopathies, cardiac arrhythmias and congestive heart failure, hepatic fibrosis, and premature death. Iron chelation therapy is used to prevent iron l...
متن کاملIron Parameters Determine the Prognosis of Critically Ill Patients: Facts and Fiction.
OBJECTIVE Because iron is both an essential and toxic micronutrient influencing the development of microbial infections, we evaluated the usefulness of iron parameters as outcome predictors in ICU patients. DESIGN Prospective clinical single-center non-interventional study. SETTING General internal medicine ICU; German University hospital. PATIENTS One hundred and twelve septic and 43 non...
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ژورنال
عنوان ژورنال: Journal of Advances in Medical and Biomedical Research
سال: 2021
ISSN: ['2676-6264']
DOI: https://doi.org/10.30699/jambs.29.133.123